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Stimulant laxatives (like senna and bisacodyl) force intestinal contractions and can cause cramping, especially when combined with semaglutide's already-slowed motility

Slowed gastric motility at 15 mg can lead to constipation, particularly if fluid and fiber intake are inadequate

High levels can be linked to high iron (possible hemochromatosis), and low levels can be a sign of functional anemia

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The study found that this class of medications significantly increases the risk of developing gastroparesis and other gastrointestinal disorders

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