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Description
The SUSTAIN 6 trial showed that subcutaneous semaglutide reduced major adverse cardiovascular events by 26% in patients with type 2 diabetes and established cardiovascular disease (hazard ratio 0.74, 95% CI 0.58-0.95)
The MASLD definition for this study relies on at least 2 elevated ALT levels and may have some degree of misclassification
While gastric bypass leads to more rapid weight loss and less regained weight than gastric sleeve, the hospital stay can be longer and the surgery can carry more risks
Similarly, GIP receptors receive tirzepatides action, enhancing meal-related insulin reactions
baseline liver and pancreatic enzyme levels
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