weight loss glp 1 agonists The role of GLP-1 receptor as agents in patients with and without type 2 diabetes A clinician's perspective 📝 GLP-1

According to the Cleveland Clinic, the higher the dose of the GLP-1 agonist, the more extreme the effects

PubMed pubmed.ncbi.nlm.nih.gov [87] Efficacy and safety of GLP-1RAs for people with obesity: A systematic review based on RCT and Bayesian network meta-analysis ScienceDirect [88] GLP-1 single, dual, and triple receptor agonists for treating type 2 diabetes and obesity: a narrative review ScienceDirect

Again, side effects from medication are always a consideration and the effects vary widely

Some researchers have pointed out that the common digestive adverse reactions of the drug (diarrhea, vomiting, loss of appetite) may be contributing to their supposed weight loss success and are not ideal ways to support metabolic health at its foundation

In diabetes care, GLP-1 receptor agonists are typically introduced as part of a stepwise treatment strategy

doi:10.1016/j.cell.2021.03.019