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Those who use GLP-1 agonists have to take it for life When asked if Ozempic, Wegovy and other GLP-1 agonist users have to continue taking it for the rest of their lives, Velazquez said yes

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Key Difference: Tirzepatide (Mounjaro/Zepbound): Dual GIP/GLP-1 agonist Semaglutide (Wegovy/Ozempic): GLP-1 agonist only Effectiveness Difference: Tirzepatide: 15-22% average body weight loss Semaglutide: 10-15% average body weight loss Semaglutide is less potent but still highly effective and significantly more affordable than brand-name tirzepatide