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These drugs didnt come out of nowhere, said Andrew Hardaway, Ph.D., a neuroscientist in the UAB Department of Psychiatry and Behavioral Neurobiology, who studies how hormones influence brain circuits that regulate appetite and reward

Some of the most remarkable findings with GLP-1 therapies were unexpected: reductions in addictive behaviors, potential cognitive improvements, and striking benefits in chronic kidney disease

Only peer-reviewed articles published in the English language were included, and studies encompassing both human and animal models, as well as preclinical and clinical investigations examining the impact of DPP-IV and SGLT2 inhibitors on cancer, especially PTC development, were considered