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Brain changes add another layer of complexity
At first glucagon attracted little attention and it was not thought to have any bearing on disease
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Bioessays 2024;46:e2400016.ArticlePubMed 55
Diabetes, Obesity and Metabolism, 27(2), 519528
Accordingly, a possible mechanism of action of GLP-1 RAs to reduce appetite and energy intake may involve interaction with neurons in the hypothalamus either directly (66, 67) or via the nodose ganglion (68), rather than a secondary consequence of slowing gastric emptying
