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Effect of race and ethnicity on vildagliptin efficacy: a pooled analysis of phase II and III studies
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5) patients with severe gastrointestinal dysfunction

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Semaglutide is contraindicated in patients with: Personal or family history of medullary thyroid carcinoma (MTC) Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Common Adverse Effects According to clinical trial data, gastrointestinal effects are most frequently reported: nausea, vomiting, diarrhea, constipation, and abdominal discomfort
