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glp 1 and hyperthyroidism Hepatic thyroid hormone signalling modulates glucose homeostasis through the regulation of GLP-1 production via bile acid-mediated FXR antagonism GLP-1RA and thyroid cancer: New
Description
Research suggests that people who hold onto more weight experience reductions in GLP-1 signaling

This effect can make you look older or more tired than you feel
Subsequent work will focus on the use of lipidated analogs of GEP44 and the possibility of one-per-week dosing

Tirzepatide is a GLP-1 receptor agonist too, but it is also a GIP (glucose-dependent insulinotropic polypeptide) receptor agonist

When you lose a significant amount of weight, you risk losing muscle along with fat
In fact, tirzepatide is a biased agonist of GIPR/GLP-1R
