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As with other medicines in the incretin-based therapy class, retatrutide's clinical trials have identified a range of side effects, most of which relate to its gastrointestinal activity

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Because GLP-1 medications can reduce appetite, people often unintentionally under-eat protein

Mahindra MP, Jie M, Mapindra MP, Rehman S, Vaughan O, Hillman S, et al

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Limitations and Concerns Regarding Sublingual Semaglutide Currently, a significant limitation is the lack of large-scale, long-term clinical trials directly comparing sublingual and injectable semaglutide
