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There have also been documented local skin reactions when using GLP-1 RAs, particularly with the long-acting formulations

Discussions and Conclusions Stopping Ozempic more than 7 days prior to surgery reduced the risk of delayed emergence from anesthesia and aspiration pneumonitis, additionally stopping 14 days prior to surgery reduced the risk of aspiration and conversion to intubation in this cohort

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[DOI] [PubMed] [Google Scholar] 48.Srinivasan D., Lofton H.F

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It represents a strategic evolution in therapeutic development, moving beyond single-target approaches to multi-receptor agonism