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semaglutide generally needs no dose adjustment Patients with kidney disease : Generally no dose adjustments needed for either medication, but monitoring is advised People with diabetes : Should be aware of the risk of diabetic retinopathy progression with rapid improvement in blood glucose control

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Yes, qualified physicians can prescribe semaglutide for weight loss in patients meeting specific clinical criteriaprimarily a BMI of 30 kg/m or higher, or 27 kg/m with weight-related comorbidities like hypertension or type 2 diabetes