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Your gut microbiome naturally produces the signals that activate your GLP-1 system

They work by mimicking the action of the natural hormone GLP-1, which helps regulate blood sugar levels by stimulating insulin secretion, reducing glucagon secretion, slowing gastric emptying, and promoting satiety

330(18):1795 Lisco G, De Tullio A, Disoteo O, Piazzolla G, Guastamacchia E, Sabb C et al (2023) Glucagon-like peptide 1 receptor agonists and thyroid cancer: is it the time to be concerned

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It has been shown that, during ischemic stress, macrophages increase their uptake of ox-LDL cholesterol, leading to increased ACAT1 activity and the formation of toxic levels of cholesterol esters [54]