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If GLP-1 and GIP have beneficial effects on blood glucose regulation, and if they are broken down by the enzyme DPP-4, then one logical pharmacological strategy is to inhibit DPP-4

The first GLP-1 drug was called Byetta or exenatide, and FDA officials approved it in 2006

10.1016/j.orcp.2015.07.003 [DOI] [PMC free article] [PubMed] [Google Scholar] 79.Yang TH, Ziemba R, Shehab N, Geller AI, Talreja K, Campbell KN, et al

For example, rather than discussing statistical risk reduction, describe how a therapy may lower the chance of certain complications over time

Your dose stays the same, but your health care provider may increase the spacing between doses

2 A ), the fetal body weights in the Sem and glucose coadministration (Sem + Glu) group remained significantly lower compared with saline-injected controls (Fig