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One cohort study published in JAMA in November 2025 found that those who halted GLP-1 use before or early in their pregnancies gained more weight and had higher risks of pregnancy complications like hypertensive disorders, diabetes and preterm delivery compared to those who hadnt used the medications before

Efficacy In the original phase 3 randomized trials for obesity, average weight reduction compared to placebo has ranged from 5.3% to 17.8% after 56 to 72 weeks (Table 1), with improvements in several obesity-related risks and complications

If the beyond-use date is 28 days from the time you first puncture the stopper, and your dose schedule would take the vial beyond that date, you may need to discard remaining medication

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Several users summarise the pattern simply: "It goes away after a few days for me sleep and blood sugar are related." anonymous "Mine were vivid when I started then went back to normal." quotidian_qt Others find the experience enjoyable: "Ive been having really long, rambling dreams mostly pleasant so I am enjoying them!" BeetleBz The key takeaway: while unusual, changes in dreaming are reported by some users and are usually temporary