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Other gastrointestinal effects to monitor include vomiting, diarrhea, abdominal pain, and constipation

They are also looking at various mouse models of inflammation, including heart disease, atherosclerosis, and liver and kidney inflammation, to establish whether the beneficial effects of GLP-1 in each case are indeed mediated through the brain

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The extension period enrolled 532 participants with BMI 35 at baseline who had completed the main 80-week study and tolerated their assigned dose of medication

It reduces the muscle activity responsible for grinding, which can decrease pain, wear on teeth, and other related symptoms

If a patient successfully lost the desired amount of weight and feels confident they can stick to the diet and exercise plan, they may begin to taper off the medication