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Among participants, AHI decreased by an average of 25.3 events per hour in trial 1 (a 50.7% reduction) and 29.3 events per hour in trial 2 (a 58.7% reduction)
Notably, in murine pancreatic -cells, GLP-1 can activate both G proteins Gs and Gq, whereas GIP selectively activates Gs (45)
They found dramatically lower depression and anxiety scores for patients treated with GLP-1s
