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Within participants with pre-existing SUDs, initiation of a GLP-1 receptor agonist was associated with reduced risk of SUD related emergency department visits (hazard ratio 0.69 (95% CI 0.61 to 0.78), NRD 8.92 (95% CI 11.59 to 6.25)), SUD related hospital admission (0.74 (0.65 to 0.85), NRD 6.23 (8.73 to 3.74)), and SUD related mortality (0.50 (0.32 to 0.79), NRD 1.52 (2.32 to 0.72)), and associated with reduced risk of the composite endpoint of the three outcomes (0.71 (0.65 to 0.79), NRD 11.79 (14.98 to 8.60)) (fig 6 and supplementary table S11)

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Preserved postprandial suppression of bone turnover markers, despite increased fasting levels, in postmenopausal women

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Studies have shown that many people regain a lot of the lost weight within months of stopping, especially if they go back to old eating patterns

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Take Action Today Ready to experience the life-changing benefits of GLP-1 medications

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Remodeling the gut microbiome is metabolically demanding

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