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Here are a few red flags to watch for: No medical screening or lab work required

Geographic Service Availability: According to Direct Meds website information current as of January 2026, the platform provides services to most US states but does not currently serve residents of Mississippi or Louisiana, where telehealth prescription of weight loss medications is restricted by state law

Within the first week, the scale goes up 2-4 pounds

A COA may confirm that a vial contains a peptide of roughly the expected mass, but it cannot confirm the synthesis was clean, that endotoxin is below a harmful level, or that an unnamed contaminant is absent

This is a positive sign that the reset achieved its goal

Most people on semaglutide deal with manageable digestive symptoms, but there are some less common, more serious side effects worth understanding before you start treatment