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The findings suggest a no-win situation in which individuals may face stigma whether they lose weight with medication, regain it, or remain at a higher weight
Leptin treatment enhanced hepatic insulin sensitivity of the MKR mice by suppression of hepatic glucose production during the hyperinsulinemiceuglycemic clamp

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These effects are often mild and most people find they lessen over time as the body adjusts to the medication

It is not yet licensed in the UK

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