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Key implications: Simplified administration may improve patient uptake Broader accessibility across diverse healthcare settings Reinforces the shift toward chronic disease models in obesity care As we move forward, the focus will not only be on efficacy but also on real-world implementation, cost considerations, and long-term outcomes

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However, because federal law does not require state-licensed pharmacies that are not outsourcing facilities to submit adverse events to FDA, many cases are likely going undocumented.FDA has also warned companies that have illegally sold unapproved drugs containing semaglutide, tirzepatide or retatrutide that are falsely labeled for research purposes or not for human consumption. These products have been sold directly to consumers for human use with dosing instructions

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