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Collagen synthesis support Glycine is the most abundant amino acid in collagen, accounting for approximately one-third of its amino acid composition

Reddy et al., 2016)

Protein constructs the scaffolding of the skin, and healthy fats keep it supple

doi: 10.1172/JCI76304

For context, semaglutide and tirzepatide do not produce dysesthesia at clinically significant rates, though a recent paper in PMC examined allodynia and dysesthesia reports across GLP-1 medications more broadly

Patients should never adjust doses without medical guidance, and treatment should be reviewed if side effects significantly impair quality of life