glp 1 age restrictions Age-Related GLP-1 Agonist Usage in Patients With Obesity and Heart Failure With Preserved Ejection Fraction Updated guidance from the PCDS

Description

GLP-1 injections work by targeting appetite regulation rather than forcing rapid weight loss

Vaz and coworkers conducted a cohort study of 46,406 individuals in Sweden (20122020), including patients with steatotic liver disease (SLD) subtypes and controls without SLD, who underwent PEth testing to assess the cumulative incidence of major liver outcomes

for the treatment of obesity, independent of diabetes status (Saxenda, a high-dose formulation of liraglutide) and Wegovy (high-dose semaglutide)

Newsome PN, Buchholtz K, Cusi K, Linder M, Okanoue T, Ratziu V, et al

Starting dose Zepbound is started at a lower dose of 2.5 mg once weekly for the first 4 weeks to prevent the risk of gastrointestinal side effects such as nausea and vomiting