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Sin embargo, los efectos secundarios gastrointestinales comunes nuseas, vmitos y diarrea pueden provocar desequilibrios de electrolitos que afectan la hidratacin, la funcin muscular y el bienestar general

The chemosensor believed to be the main receptor of bile acids is TGR5, also known as GPR131 or GPBAR1 among other names
TGF-1 was used as a positive control for EMT

[2] This dual action helps to regulate blood glucose levels without causing significant hypoglycaemia when used as monotherapy, though the risk increases when combined with insulin or sulfonylureas

Beyond gastrointestinal issues, CagriSema showed a pattern consistent with the known GLP-1 receptor agonist class

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