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In endometrial cancer cells, liraglutide induces an upregulation in progesterone receptor (PGR) mRNA levels, promotes its protein expression, markedly enhances phosphorylated AMPK levels, and downregulates its downstream effector molecule p-P71S6K, ultimately inhibiting cell viability [58]

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Comparative Effectiveness of Once-Weekly Glucagon-Like Peptide-1 Receptor Agonists With Regard to 6-Month Glycaemic Control and Weight Outcomes in Patients With Type 2 Diabetes