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Genitourinary syndrome of menopause (GSM) is driven by low or fluctuating oestrogen and is characterised by vulvovaginal dryness, irritation, dyspareunia, recurrent infections/urinary symptoms, and tissue fragility

Monitoring and adjustments Track your weight weekly, not daily

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The average incidence rate of any retinal adverse event in these studies was approximately 5.6 per 1000 person-years or 0.6%, lower than the present study and also lower than previously reported in type 2 diabetes cohorts [23, 24]

Absolute contraindications to GLP-1 receptor agonists include: Personal history of medullary thyroid carcinoma Family history of medullary thyroid carcinoma Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Pregnancy (for weight management indications) Severe gastrointestinal disease, including gastroparesis Patients should be specifically questioned about these conditions during pre-treatment evaluation
