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This personalized approach moves beyond one-size-fits-all guidelines

As an investigational agent, the full safety profile of retatrutide has not yet been established

Cold sensitivity alone is not a reason to discontinue semaglutide, but it should inform dose personalization and ongoing monitoring

Beyond their effectiveness in glycemic control, these therapies also promote weight loss, making them beneficial for patients with overweight or obesity alongside type 2 diabetes

2,3 Wegovy (semaglutide 2.4 mg), a once-weekly injectable medication, works by mimicking the natural hormone GLP-1 released by the gut after eating

Symptoms typically peak during the first week and then gradually diminish