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Acute pancreatitis: I would not recommend tirzepatide in people with a history of pancreatitis, and it should be withdrawn and not restarted in patients who have an episode whilst on treatment
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This mismatch is why early dosing often triggers or worsens nausea, fatigue, and gastrointestinal upset within the first 24 to 48 hours
Over 40 weeks, all three doses (5 mg, 10 mg, and 15 mg) demonstrated statistically significant and clinically meaningful superiority over placebo
Professional Medical Disclaimer This article is educational and does not constitute medical advice
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