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This is a factor that many dosing guides overlook

Your plunger should sit exactly on the midpoint between 70 and 80
Thyroid issues sometimes show up as fatigue, but tumors are usually accompanied by a lump or swelling in the neck, hoarseness, trouble swallowing, or persistent neck pain
These usually resolve as your body acclimates

Maybe try to use a search?
While further studies are needed to determine the exact cause, it may be linked to fluctuating blood sugar levels, diabetic retinopathy, low blood sugar, and other issues common to patients taking the medication