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Supplementary Table 16 (download XLSX The predictions of multi-task neural-network model ensemble for glucagon-like peptide-1 orthologues sequences collected from the NCBI database

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Type 1 is an autoimmune condition requiring insulin replacement, and GLP-1 medications do not address the underlying pancreatic beta-cell destruction

Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2
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However, it is important to emphasize that tirzepatide is not approved for, nor specifically designed to treat, autoimmune diseases