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Most people experience peak nausea during the first 24 weeks at a new dose, with gradual improvement over the following 23 weeks as their digestive system adapts

Journal of Endocrinology and Metabolism, 3(12), 715
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doi: 10.1161/atv.0000615456.97862.30 112 HusainMBainSCJeppesenOKLingvayISrrigRTreppendahlMBet al

A loss of appetite and a decrease in calorie consumption can promote weight loss