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Although all agents presented distinct benefits, side effects such as gastrointestinal discomfort with orlistat and GLP-1 receptor agonists, and potential dependency with phentermine, necessitate tailored treatment approaches.This review highlights the importance of integrating pharmacotherapy with lifestyle interventions to achieve sustainable weight management and identifies areas for future research to optimize therapeutic outcomes for individuals with obesity.

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Racial and ethnic disparities Minority populations, particularly Black, Hispanic, and Indigenous groups, face disproportionate rates of obesity but often encounter systemic barriers in accessing treatment