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If cost is a limiting factor and you're forced to choose one, semaglutide delivers more total weight loss per dollar spent

| Do you lose more weight on the higher doses of Ozempic

Clinical data suggests tirzepatide produces greater average weight loss, and its approved dose ceiling of 15mg weekly is higher than semaglutide's 2.4mg maximum

and the MC4R rs17782313 variant modulates melanocortin signaling

only for diabetes, not for weight loss

However, people with MS who also have obesity or type 2 diabetes may be candidates for GLP-1 therapy, says Alan David Kaye, MD, PhD, a professor and the vice chair of research in the anesthesiology department at LSU Health in Shreveport, Louisiana