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Tirzepatide should be titrated in 2.5 mg increments no sooner than every 4 weeks, based on tolerability and response, up to a maximum of 15 mg

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Side effect patterns when transitioning between GLP-1 medications The most common side effects during the switch are gastrointestinal: nausea, vomiting, diarrhea, constipation, and abdominal discomfort

Upon suspicion of a metoclopramide-induced RLS-like reaction, treatment interruption is warranted, and the avoidance of other dopamine antagonists may be advisable in the long term

This can help you minimize eating out of boredom, stress, or habit