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The cause of the eye problems is thought to be due to Dupixent blocking interleukin-13 (IL-13), an inflammatory protein that also stimulates the production of goblet cells

[7] [8] Symptoms include sudden pain in the upper right abdomen, fever, jaundice (yellowing of the skin or eyes), pale stools, or dark urine

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During the acquisition phase (days 14), each mouse performed four trials daily with a 15-minute inter-trial interval