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That's pretty significant

5 The patient was premedicated with midazolam 2 mg iv and preoxygenated with 100% oxygen for three minutes

Gq activates phospholipase C (PLC), leading to hydrolysis of phosphoinositol diphosphate (PIP2) into products like IP3 and DAG, resulting in elevated Ca levels

The contribution of glucagon receptor activation to intestinal fluid secretion has been proposed but is not yet established, and should be regarded as speculative at this stage

She liked the Ro team and the medication

Potential benefits include complementary weight loss and improved glycaemic control, whilst risks include dehydration, excessive caloric restriction, gastrointestinal side effects, and rare serious complications such as pancreatitis