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A separate nationwide cohort of older Danish patients found an 11% reduced dementia risk on GLP-1s

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53 The above findings indicate that GLP-1RAs inhibit food intake and cause weight loss mainly by acting on different brain regions, which also supports the evidence of long-acting GLP-1RAs penetrating incomplete BBB in certain areas

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Bottom line: An overdose of tirzepatide primarily manifests as severe digestive upset and metabolic imbalances that require professional medical attention