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So far, the mechanisms underlying the protective effects of GLP-1RA in respiratory disease are not fully understood

GLP-1, or glucagon-like peptide-1, is a hormone produced in the gut that helps lower blood sugar levels by stimulating insulin release and slowing stomach emptying

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Obesity is the major risk factor for OSA, primarily due to the deposition of adipose tissue in the pharyngeal walls, tongue, and abdominal cavity, which increases upper airway collapsibility and reduces lung volume during sleep, predisposing individuals to airway obstruction [11, 12]

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Selective spectrum antibiotic modulation of the gut microbiome in obesity and diabetes rodent models