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Therefore, emphasis should be placed on combining energy-restriction with a high protein diet and physical activity, to provide the maximal anabolic stimulus, ensuring weight loss is not associated with loss of muscle mass, or, more importantly, muscle strength [67, 68]

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A systematic literature review was conducted with the help of a librarian (VC) based on strategy decided upon by the consensus group, and peer reviewed by a second information science professional (Supplementary File 1)

With more structural and dynamics studies on class B GPCRs, the activation process from inactive to active states via an intermediate state, i.e., allosteric communication between extracellular peptide binding and intracellular G protein coupling, will be better understood

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