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In this review, we aimed to summarize the changes in endogenous GLP-1 levels and their association with weight loss after MBS, describe the effects of GLP-1-RA use on weight loss after MBS, and emphasize metabolic adaptations in light of the recent literature

This breaks down how dosing frequency changes peak exposure, accumulation, and how to read the protocol.

It explains how each works, evidence and safety differences, and practical guidance for choosing a clinician-supervised path.

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