switching semaglutide to tirzepatide from Impact of the CVS GLP-1

Levels naturally decline with age

The gastrointestinal side effects may also prove more problematic for older adults, particularly those with existing digestive conditions or those taking multiple medications that interact with gut function

10.2337/diacare.25.7.1123 [EL 1

The JAMA Internal Medicine paper describes when to consider weight-loss medications as part of your patients treatment plan, including an easy-to-follow flow chart for additional guidance

In addition, fetal congenital abnormalities in animal models of GLP1RA use in pregnancy are reported by both Eli Lilly and Novo Nordisk in the prescribing information for Mounjaro (tirzepatide, a dual Glucose-dependent insulinotropic polypeptide [GIP] and GLP1R agonist

If that distinction matters to you, it should factor into your decision