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Carriers of certain alleles show faster metabolic adaptation and greater fat-loss acceleration, while others may require longer dose escalation to reach optimal metabolic effects

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Semaglutide works by slowing stomach emptying and reducing hunger signals, leading to meaningful weight loss in clinical trials within weeks rather than months

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10.1124/jpet.104.073890 [DOI] [PubMed] [Google Scholar] 25.Dutour A, Abdesselam I, Ancel P, Kober F, Mrad G, Darmon P, et al

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