tirzepatide and letrozole Not 👏 A 👏 Fad ! 👏 Notice these trials are all using ?!, There are active recently opened clinical/human trials (& more coming !) testing tirzepatide in breast-cancer populations. Why ? Letrozole 5 mg- LETROZIV 5

2022;13(Suppl 1):517

There is no clinical evidence that tapering provides any benefit before switching

Retatrutide The side effects of retatrutide are almost identical to the ones experienced by tirzepatide users, but since retatrutide includes the third hormone, glucagon, they may be more intense

Although tirzepatide was initially developed to treat type 2 diabetes, it has demonstrated significant effects on weight loss and has been rapidly adopted under the brand names Mounjaro (for diabetes) and Zepbound (for obesity)

The standard semaglutide dosing protocol starts at 0.25mg weekly and titrates up to 2.4mg over approximately 16 to 20 weeks

By extending earlier preclinical work on GLP-1 receptor agonists and alcohol intake to a task that directly assesses the subjective effects of alcohol, these findings provide important context for interpreting clinical observations of reduced drinking behavior among individuals receiving GLP-1 receptor-based therapies