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Understanding the importance of adherence to the prescribed dosing schedule cannot be overstated

In this issue of Diabetologia , Hogan and colleagues report an improvement of psoriasis in three obese patients with type 2 diabetes several weeks after the initiation of therapy with the glucagon-like peptide-1 (GLP-1) receptor (GLP-1R) agonists exenatide and liraglutide [2]

Despite the great advantages of modern in vitro models, some limitations, such as the restricted cell types present in endometrial models, need to be addressed

doi:10.1007/s00592-025-02525 71

In mammals, the first step of systemic NAD + biosynthesis depends on the salvage pathway in which nicotinamide (NAM), a water-soluble vitamin B3, is converted to NMN by NAMPT

Tesofensine, a monoamine reuptake inhibitor for the treatment of obesity
