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Postmenopausal women face particularly high UTI risk because declining estrogen levels thin the vaginal and urethral tissues, reduce protective Lactobacillus populations, and alter urinary pH

2,3 Furthermore, several cardiovascular outcome trials (CVOT) suggest GLP-1 RAs confer a mortality benefit, with significant reductions in major adverse cardiovascular events, all-cause mortality, heart failure severity, and worsening kidney function

[DOI] [PMC free article] [PubMed] [Google Scholar] 41.Sze L, Purtell L, Jenkins A, Loughnan G, Smith E, Herzog H, et al

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Drug manufacturers dont typically list fatigue as a side effect caused by their medications, but many people who use them report feeling unusually tired