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Our analysis of the collected data revealed that psychiatric AEs were most frequently reported in relation to diabetes ( n = 5,286, 64.15%) and weight control ( n = 332, 4.03%)
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In the SURPASS-4 trial, tirzepatide significantly decreased blood pressure, body weight, and HbA1c, and its dual-receptor agonism improved lipid profiles, increased insulin secretion, reduced inflammation, and promoted endothelial integrity (32)
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