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According to NICE guidance, these treatments are typically recommended for adults with a body mass index of 30 kg/m or above, or 27 kg/m with weight-related health conditions, when used as part of specialist weight management services

However, these ingredients do not activate the GLP-1 receptor in the same way prescription semaglutide or tirzepatide do, and bioavailability data remains limited

Some patients have instead looked to compounded versions of the weight loss drug, which typically come in vials and are less expensive