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Your microbiome adjusts, gas subsides, and you avoid an abrupt fiber bomb. By day four your gut usually says, Were good, bring on the full dose. Pair the chew with protein-rich meals

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Side effects most often appear: This timing is typical and doesnt necessarily mean the medication isnt a good fit

Surprisingly, the SURMOUNT-5 trial found that fewer people discontinued tirzepatide due to side effects (2.7%) compared to semaglutide (5.6%)

The increased risks of peripheral vestibular disorders, dizziness, and hearing impairment associated with GLP-1 RA use were generally consistent across most subgroups, except among participants of Black and Asian races

A 2021 study even found that tooth loss, dry mouth, and having three or more oral problems as an older person are all tied to higher all-cause mortality