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Free fatty acids produce insulin resistance and activate the proinflammatory nuclear factor-kappaB pathway in rat liver

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Davies M, Pieber TR, Hartoft-Nielsen ML, Hansen OK, Jabbour S, Rosenstock J

In rare cases it could also cause pancreatitis - inflammation of pancreas

Exploring the mechanisms of receptor synergy and its influence on weight loss and glycemic control could help in designing more targeted and potent agonists