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Generalized disease can involve all skeletal muscles, especially: Eye muscles: diplopia, blurred vision [6] Bulbar muscles: dysarthria, difficulty chewing and/or swallowing, dyspnea Proximal muscles: difficulty standing from a chair, climbing stairs, brushing hair [6] Respiratory muscles: dyspnea, respiratory failure Localized disease most commonly affects the eye muscles

Discontinuation Trends and Persistence Patterns Despite the clinical benefits of GLP-1 receptor agonists, discontinuation remains a challenge

Some people end up losing so much weight they have to go off the drug, Belluz added

As a result, patients experience a reduction in fat cell size, leading to targeted fat loss and improved body contouring

The relatively long run-in (20 weeks) in STEP 4 may have resulted in a selected population that was already responding to the drug and tolerating semaglutide before being randomized

Greek yogurt provides protein and probiotics while offering a lower-calorie dairy option than traditional cheese