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For example, in the oral contraceptive (OC)-SELENA and hormone replacement therapy (HRT)-SELENA studies, 60% and 50% of patients receiving a placebo, respectively, experienced at least one mild or moderate flare during the 12 month follow-up periods [12, 17]

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10.1038/s41586-018-0620-2 152 VatanenT.De BeaufortC.MarcovecchioM

Evidence remains investigational and evolving

Furthermore, trial results will be published in peer-reviewed journals and disseminated at relevant conferences and to the healthcare professionals and public via educational talks, including any publication restrictions